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All 8 posts Subject: 1-(2,5-Dimethoxy-4-(CF3)phenyl)-2-aminopropane Please login to post Down

pHarmacist
(Hive Addict)
04-27-03 12:46
No 429739
User Picture       1-(2,5-Dimethoxy-4-(CF3)phenyl)-2-aminopropane

1-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-aminopropane: A Potent Serotonin 5-HT2A/2C Agonist
David E. Nichols, Stewart Frescas, Danuta Marona-Lewicka, Xuemei Huang, Bryan L. Roth, Gary A. Gudelsky, J. Frank Nash;
J. Med. Chem.; 1994; 37(25); 4346-4351.

____ __ _

Full-text: http://pharmacist8.tripod.com/para-CF3.pdf

Accept No Imitations, There Can Only Bee One; www.the-hive.ws

yellium
(I'm Yust a Typo)
04-27-03 13:00
No 429741
      Any plans to synth that compound?

Any plans to synth that compound?

pHarmacist
(Hive Addict)
04-27-03 13:06
No 429743
User Picture       Yes, I'll try to find some time...

I've got exams now, have no time to even use TFSE sometimes, but I'll try to synth it after this madness. hehe, have fun Yellium... -CF3 function always intrigued me...

Accept No Imitations, There Can Only Bee One; www.the-hive.ws

yellium
(I'm Yust a Typo)
04-27-03 13:29
No 429747
      Post 122784 : Are you sure?

Post 122784 (dormouse: "Bromo-benzodifuranyl-isopropylamine -Lilienthal", Serious Chemistry):

Are you sure? 2 weeks to get reasonably 'down' is a long time..

GC_MS
(Hive Addict)
04-27-03 16:20
No 429767
User Picture       haha!

Haha, yeah, two weeks is a long end... wink I have the article here as well, but I regret the use of some expensive chemicals, especially for the trifluoromethylation. I have done some research in the library to find cheaper alternatives, but most searches were in vain. I had some ideas when I was doing the searching, but unless I can find my notes again, I can't give the exact details.
What intrigued me more about this substance was how and why it is that more potent, but also if there have been human trials. I don't know if the information from TFSE is reliable. Two weeks sounds alot. That is about 14 times longer then DOB smile .

The faster you run, the quicker you die.

moo
(Hive Bee)
04-27-03 20:49
No 429810
      I've got the impression that Drone liked to...

I've got the impression that Drone liked to talk a lot. I'm not saying that I really knew anything about him but on the other hand I don't know how realiable his information on the subject is. Drug folklore is filled with myths, not least because of people who like to boast with them. Maybe it would be wiser to try 2C-TFM first and have a good supply of downers on hand.

Reading this thread might be worth as well: Post 263890 (poix: "alkylation of quinones", Novel Discourse)

Chimimanie
(Hive Bee)
04-27-03 21:43
No 429818
User Picture       I second that

I really dont think it stay this long, it could not be possible. I have no pharmaceutical knowledge, but I dont trust drone neither.

And yes, lets try 2C-TFM bee4.

Poix has got a good idea in that thread moo, it would bee great if some experimentation could bee done on this wink .

cool

Rhodium
(Chief Bee)
04-28-03 12:12
No 429967
User Picture       2C-TFM

Rumor has it that 2C-TFM is more stimulating than the 4-halo analogs, and that the duration of action is around 12h. Unfortunately, I have no further details.

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	All 8 posts		Subject: 1-(2,5-Dimethoxy-4-(CF3)phenyl)-2-aminopropane		Please login to post		Down


		pHarmacist (Hive Addict) 04-27-03 12:46 No 429739				1-(2,5-Dimethoxy-4-(CF3)phenyl)-2-aminopropane
						1-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-aminopropane: A Potent Serotonin 5-HT2A/2C Agonist David E. Nichols, Stewart Frescas, Danuta Marona-Lewicka, Xuemei Huang, Bryan L. Roth, Gary A. Gudelsky, J. Frank Nash; J. Med. Chem.; 1994; 37(25); 4346-4351. ____ __ _ Full-text: http://pharmacist8.tripod.com/para-CF3.pdf Accept No Imitations, There Can Only Bee One; www.the-hive.ws



		yellium (I'm Yust a Typo) 04-27-03 13:00 No 429741				Any plans to synth that compound?
						Any plans to synth that compound?



		pHarmacist (Hive Addict) 04-27-03 13:06 No 429743				Yes, I'll try to find some time...
						I've got exams now, have no time to even use TFSE sometimes, but I'll try to synth it after this madness. hehe, have fun Yellium... -CF3 function always intrigued me... Accept No Imitations, There Can Only Bee One; www.the-hive.ws



		yellium (I'm Yust a Typo) 04-27-03 13:29 No 429747				Post 122784 : Are you sure?
						Post 122784 (dormouse: "Bromo-benzodifuranyl-isopropylamine -Lilienthal", Serious Chemistry): Are you sure? 2 weeks to get reasonably 'down' is a long time..



		GC_MS (Hive Addict) 04-27-03 16:20 No 429767				haha!
						Haha, yeah, two weeks is a long end... I have the article here as well, but I regret the use of some expensive chemicals, especially for the trifluoromethylation. I have done some research in the library to find cheaper alternatives, but most searches were in vain. I had some ideas when I was doing the searching, but unless I can find my notes again, I can't give the exact details. What intrigued me more about this substance was how and why it is that more potent, but also if there have been human trials. I don't know if the information from TFSE is reliable. Two weeks sounds alot. That is about 14 times longer then DOB . The faster you run, the quicker you die.



		moo (Hive Bee) 04-27-03 20:49 No 429810				I've got the impression that Drone liked to...
						I've got the impression that Drone liked to talk a lot. I'm not saying that I really knew anything about him but on the other hand I don't know how realiable his information on the subject is. Drug folklore is filled with myths, not least because of people who like to boast with them. Maybe it would be wiser to try 2C-TFM first and have a good supply of downers on hand. Reading this thread might be worth as well: Post 263890 (poix: "alkylation of quinones", Novel Discourse)



		Chimimanie (Hive Bee) 04-27-03 21:43 No 429818				I second that
						I really dont think it stay this long, it could not be possible. I have no pharmaceutical knowledge, but I dont trust drone neither. And yes, lets try 2C-TFM bee4. Poix has got a good idea in that thread moo, it would bee great if some experimentation could bee done on this.



		Rhodium (Chief Bee) 04-28-03 12:12 No 429967				2C-TFM
						Rumor has it that 2C-TFM is more stimulating than the 4-halo analogs, and that the duration of action is around 12h. Unfortunately, I have no further details.

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