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All 2 posts   Subject: reduction of isonicotinic acid   Please login to post   Down

 
    SilverSurfer
(Hive Bee)
12-05-03 17:32
No 474839
      reduction of isonicotinic acid     

Reffering to demerol synth
[url=https://www.rhodium.ws/chemistry/pethidine.html]

Why isnt the reduction of the isonicotinicacid step one,
instead reducing it before methylating

Is there recently a more practically way of reducing it?

The only purpose of your life may be to serve as a warning to others http://www.despair.com
 
 
 
 
    Rhodium
(Chief Bee)
12-05-03 21:24
No 474871
User Picture 
      why     

N-Alkyl-pyridinium salts are more easily reduced than the plain pyridines.
 
 

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