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All posts   Subject: Imines from alcohols in one pot.   Please login to post  

 
    Rhodium
(Chief Bee)
01-26-04 06:46
No 484617
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      Imines from alcohols in one pot.
(Rated as: good read)
    

In Situ Oxidation-Imine Formation-Reduction Routes from Alcohols to Amines
Leonie Blackburn and Richard J. K. Taylor
Org. Lett. 3(11) 1637-1639 (2001) (https://www.rhodium.ws/pdf/alcohol2amine.pscbh.pdf)
DOI:10.1021/ol015819b



Abstract
Manganese dioxide is employed as an in situ oxidant for the one-pot conversion of alcohols into imines. In combination with polymersupported cyanoborohydride (PSCBH), a one-pot oxidation-imine formation-reduction sequence is reported. This procedure enables alcohols to be converted directly into both secondary and tertiary amines.

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