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All 4 posts   Subject: Converting heliotropin to isosafrole or safrole   Please login to post   Down

 
    lastchance
(Stranger)
02-26-04 21:31
No 491284
      Converting heliotropin to isosafrole or safrole     

Is there any way to to this?  Any responses would be appreciated.
 
 
 
 
    Kinetic
(Hive Bee)
02-26-04 21:50
No 491292
      Wittig     

Yes. You musn't have looked very hard. There are posts here specifically on the use of the Wittig reaction to convert piperonal (heliotropin) to isosafrole. There is also at least one page on Rhodium's site dedicated to the same. If you're really lazy click here (https://www.rhodium.ws/chemistry/isosafrole.piperonal.html).
 
 
 
 
    cublium
(Hive Bee)
02-27-04 06:41
No 491363
      It's possible but probably not worth it as i...     

It's possible but probably not worth it as i can see from link above.Convert to nitropropene and reduce that to something or convert to ketone.
 
 
 
 
    GC_MS
(Hive Addict)
02-27-04 07:05
No 491366
User Picture 
      I really don't see what this thread is doing...     

I really don't see what this thread is doing in the Serious Chemistry dpt.... If you can get a hold on acetic anhydride, a practical and in the scientific literature well described procedure would be via the Perkin reaction.

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