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All posts   Subject: Structure-Activity Relationships in Cannabinoids   Please login to post  

 
    Rhodium
(Chief Bee)
03-16-04 19:45
No 495536
User Picture  		      Structure-Activity Relationships in Cannabinoids
(Rated as: excellent) 		    

Structure-Activity Relationships in Cannabinoids
Raj K. Razdan
Pharmacological Reviews Vol. 38, No. 2, 75-149 (1986) (https://www.rhodium.ws/djvu/cannabinoid-sar.djvu)

I. Introduction
II. Drug development: an overview
III. Assessment of biological activity
A. Dog ataxia test
B. Monkey behavioral test
C. Mouse ring immobility assay
D. Tetrahydrocannabinol-seizure susceptible (THC-SS) rabbit model
E. Spontaneous activity and body temperature in mice
F. Drug discrimination procedure
G. Conclusions
IV. Structure-activity relationships (SAR)
A. SAR in man
B. SAR in animals
V. Conclusion
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