Hive Methods Discourse

	Main Index Search Register Login Who's Online FAQ Links
	Main Index Search Register Login Who's Online FAQ Links

	1 Online, 0 Active		You are not logged in

This is a historical archiveThe forum is read-only. Private information has been removed. It is not possible to login.

	Methods Discourse

All 5 posts Subject: methylamine ratios Please login to post Down

psytech
(Hive Bee)
05-27-04 01:28
No 509834
      methylamine ratios

On Rhodiums sites mdma from nabh4 synth uses a ratio of 2 moles methylamine to 1 mole mdp2p. Then for the synth for meth uses a ratio of 3.2 moles methylamine to 1 mole p2p. My question is why the big diffrence.

Megatherium
(Hive Bee)
05-27-04 01:39
No 509838
      Correct your post's title, will you.

Correct your post's title, will you (for TFSE's sake): methylamine.

On Rhodiums sites mdma from nabh4 synth uses a ratio of 2 moles methylamine to 1 mole mdp2p. Then for the synth for meth uses a ratio of 3.2 moles methylamine to 1 mole p2p. My question is why the big diffrence.

It 's just excess. With Le Chateliers principle in mind, excess methylamine (obviously the cheap reagent) is used to drive the equilibrium (imine formation) to the right. Molecular sieves (absorption of the water ) are used for the same reason. It 's all a matter of equilibrium. You wouldn't like to reduce the propanone, would you?

Aztec fanclub member

psytech
(Hive Bee)
05-27-04 02:25
No 509845
      i know its excess

I know its in excess, but why isn't the same ratio applied to both ketones. And (btw) I tried the TFSE first. Here at the Hive its all about improving methods, and understanding the principles behind those methods. So dont get so uptight.Thanks for the input but you really did'nt help increase knowledge base. The insight I was inquiring about was, in decreasing the amount of methylamine in NaBH4 Reductive Alkylation of P2P.If you havent't performed the reduction, you really have no experience, theory is all well and fine, but I live in the real world, and all reagents are precious.

Rhodium
(Chief Bee)
05-27-04 04:00
No 509864
User Picture       archive of stuff "found to work"

I believe the difference is due to how much methylamine the particular author had on hand (compared to the ketone) rather than an actual requirement for each of the ketone. The methods on my page are mostly syntheses "found to work" rather than being "fully optimized" in regards to reactant/solvent ratios, reaction times etc.

^{The Hive - Clandestine Chemists Without Borders}

psytech
(Hive Bee)
05-27-04 17:22
No 509948
      that makes more sense

Thanks Rhodium, so I'll have to try it myself, I'll report back.

	https://the-hive.archive.erowid.org	the-hive@erowid.org



Powered by Dirty Bong Water^TM Version 3.10.0, (C) 2021 - 2022, Underground Chemists Foundation
Links Erowid Rhodium

	All 5 posts		Subject: methylamine ratios		Please login to post		Down


		psytech (Hive Bee) 05-27-04 01:28 No 509834				methylamine ratios
						On Rhodiums sites mdma from nabh4 synth uses a ratio of 2 moles methylamine to 1 mole mdp2p. Then for the synth for meth uses a ratio of 3.2 moles methylamine to 1 mole p2p. My question is why the big diffrence.



		Megatherium (Hive Bee) 05-27-04 01:39 No 509838				Correct your post's title, will you.
						Correct your post's title, will you (for TFSE's sake): methylamine. On Rhodiums sites mdma from nabh4 synth uses a ratio of 2 moles methylamine to 1 mole mdp2p. Then for the synth for meth uses a ratio of 3.2 moles methylamine to 1 mole p2p. My question is why the big diffrence. It 's just excess. With Le Chateliers principle in mind, excess methylamine (obviously the cheap reagent) is used to drive the equilibrium (imine formation) to the right. Molecular sieves (absorption of the water ) are used for the same reason. It 's all a matter of equilibrium. You wouldn't like to reduce the propanone, would you? Aztec fanclub member



		psytech (Hive Bee) 05-27-04 02:25 No 509845				i know its excess
						I know its in excess, but why isn't the same ratio applied to both ketones. And (btw) I tried the TFSE first. Here at the Hive its all about improving methods, and understanding the principles behind those methods. So dont get so uptight.Thanks for the input but you really did'nt help increase knowledge base. The insight I was inquiring about was, in decreasing the amount of methylamine in NaBH4 Reductive Alkylation of P2P.If you havent't performed the reduction, you really have no experience, theory is all well and fine, but I live in the real world, and all reagents are precious.



		Rhodium (Chief Bee) 05-27-04 04:00 No 509864				archive of stuff "found to work"
						I believe the difference is due to how much methylamine the particular author had on hand (compared to the ketone) rather than an actual requirement for each of the ketone. The methods on my page are mostly syntheses "found to work" rather than being "fully optimized" in regards to reactant/solvent ratios, reaction times etc. ^{The Hive - Clandestine Chemists Without Borders}



		psytech (Hive Bee) 05-27-04 17:22 No 509948				that makes more sense
						Thanks Rhodium, so I'll have to try it myself, I'll report back.

All 5 posts	End of thread	Top