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All 3 posts Subject: Heterocodeine Please login to post Down

camxyl
(Stranger)
10-05-04 21:05
No 534581
User Picture       Heterocodeine

Does anyone know anything interesting about Heterocodeine? [Morphine with an extra Methyl group on the opposite hydroxy group to codeine]

Apparantely its 5x the potency of morphine and more addictive [I'm guessing because of the lipophilicity and entering the brain more readily].

Its just strange as there doesn't seem to be much info on pubmed or google yet its such a simple modification of morphine. [Maybe I'm just not looking hard enough or is it called something else?]

- Camxyl

Stonium
(BEE-OTCH)
10-05-04 22:56
No 534593
User Picture       According to this source, heterocodeine has a...

According to this source, heterocodeine has a six-fold increase in activity:

http://wiz2.pharm.wayne.edu/module/opioid.html

_{Dissent is the highest form of patriotism.
-Howard Zinn}

camxyl
(Stranger)
10-05-04 23:13
No 534594
User Picture       I was also told that it has more potential...

I was also told that it has more potential side effects but I'm not sure whether to take that as "it's less suitable for medical use" due to its more addictive properties?

Maybe its more toxic to the body.

- Camxyl

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	All 3 posts		Subject: Heterocodeine		Please login to post		Down


		camxyl (Stranger) 10-05-04 21:05 No 534581				Heterocodeine
						Does anyone know anything interesting about Heterocodeine? [Morphine with an extra Methyl group on the opposite hydroxy group to codeine] Apparantely its 5x the potency of morphine and more addictive [I'm guessing because of the lipophilicity and entering the brain more readily]. Its just strange as there doesn't seem to be much info on pubmed or google yet its such a simple modification of morphine. [Maybe I'm just not looking hard enough or is it called something else?] - Camxyl



		Stonium (BEE-OTCH) 10-05-04 22:56 No 534593				According to this source, heterocodeine has a...
						According to this source, heterocodeine has a six-fold increase in activity: http://wiz2.pharm.wayne.edu/module/opioid.html _{Dissent is the highest form of patriotism. -Howard Zinn}



		camxyl (Stranger) 10-05-04 23:13 No 534594				I was also told that it has more potential...
						I was also told that it has more potential side effects but I'm not sure whether to take that as "it's less suitable for medical use" due to its more addictive properties? Maybe its more toxic to the body. - Camxyl

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