Main Index   Search   Register   Login   Who's Online   FAQ   Links
	2 Online, 0 Active		You are not logged in

This is a historical archiveThe forum is read-only. Private information has been removed. It is not possible to login.

	General Discourse

	All posts		Subject: New m-Opioid Receptor Agonists .		Please login to post

		KLt (Newbee) 11-09-04 06:36 No 540593				New m-Opioid Receptor Agonists . (Rated as: good read)
						Chem. Pharm. Bull. 49(10) 1314—1320 (2001) Vol. 49, No. 10 New m-Opioid Receptor Agonists with Piperazine Moiety Teruo KOMOTO,*,a,c Tomomi OKADA,a Susumu SATO,a Yasuhiro NIINO,b Tetsuo OKA,b and Takao SAKAMOTO*,c Abstract New m-opioid receptor (MOR) agonists containing piperazine and homopiperazine moieties in the structures were synthesized and their affinities to and agonist potencies on MOR were evaluated. Among the synthesized compounds, 4-[4-(2-methoxyphenyl)piperazin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide (20Aa) showed the highest affinity to the human MOR expressed in Chinese hamster ovary (CHO)-K1 cells, and the highest agonist potency on the MOR in isolated guinea-pig ileum preparation. Edit:references added

	All posts		End of thread

	https://the-hive.archive.erowid.org		the-hive@erowid.org
Powered by Tidal Power 6.19.3, (C) 2020 - 2021, SoftCouch-Soft United
Links     Erowid     Rhodium

Date: 05-03-24, Release: 1.6 (10-04-15), Links: static, unique