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All 6 posts | Subject: Sedative Ureides | Please login to post | Down | |||||
Bwiti (PVC-Analog Taste-Tester) 10-18-04 05:16 No 536297 |
Sedative Ureides | |||||||
Carbromal(Uradal, Adalin) 1 mole of α-bromo-α-ethyl butyryl bromide is mixed with dry urea(1 mole) and heated on a steam bath for several hours. Precautions must be taken to keep steam and atmospheric H2O from the reaction vessel. Cool, allow to solidify, wash with H2O, and recrystallize from alcohol. Dose: (sedative) 300 to 500mg, (hypnotic) 700 to 950mg, mp 116-118°C. This drug is less potent than the barbiturates, but it is less toxic, extremely well tolerated, has a wide margin of safety, and acts rapidly. Bromural(Bromovaletone) This is made the same way that carbromal is made, except that the intermediate is α-bromo-isovaleryl bromide. The 1 to 1 molar ratio and everything else remains unchanged Yields colorless crystals, mp: 147-149°C. This is a rapid-action, short-duration hypnotic. It is well tolerated and has a low toxicity. Dose: 300-600mg. Reference: “Recreational Drugs” by Professor Buzz These synths are so easy that even Professor Buzz can’t fuck them up! Are either bromo-intermediates easily obtainable? I can’t find my merck index CD, and a patent search at http://ch.espacenet.com/espacenet/ch/en/e_net.htm didn’t turn-up dick, so I’m wondering how they’re made, do they have any synonyms, what their properties are? Are there other ureides or analogs that could possibly have sedative effects? Peace! Love My Country, Fear My Government |
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Rhodium (Chief Bee) 10-18-04 07:12 No 536309 |
The synthesis of Bromural and its precursors | |||||||
The synthesis of Bromural and its precursors can be found on page 999 in Vogel's "Practical Organic Chemistry", 3rd Ed (https://www.rhodium.ws/chemistry/vogel3.html) The precursor α-bromoacyl bromides are likely not commercially available, and has to be made from the corresponding carboxylic acid through the well-known Hell-Volhard-Zelinsky Reaction (http://www.organic-chemistry.org/namedreactions/hell-volhard-zelinsky-reaction.shtm) The Hive - Clandestine Chemists Without Borders |
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Bwiti (PVC-Analog Taste-Tester) 10-19-04 00:58 No 536501 |
couldn't find.. | |||||||
Page 999 of Vogel's 3rd edition had nothing on the chem of interest, and the Hell-Volhard-Zelinsky Reaction is useless to the simple chemist. Love My Country, Fear My Government |
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Rhodium (Chief Bee) 10-21-04 08:42 No 536940 |
Bromural - Bromisovalum (Rated as: excellent) |
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The synthesis is definitely on page 999 in Vogel's "Pracical Organic Chemistry" (https://www.rhodium.ws/djvu/vogel/practical-organic-chem_224_0001_2.djvu) Here it follows (minus footnotes and pointers to equipment & precursor preparation):
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Captain_America (Über-Führer die Ironie) 10-21-04 11:39 No 536946 |
bwiti | |||||||
How would you describe the effects of this compound? |
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Bwiti (PVC-Analog Taste-Tester) 10-25-04 18:34 No 537741 |
shit.. | |||||||
Oops! The menu above took me to the right place just as long as I selected 1024 as the destination page.. Would the compounds of chloro or iodo be easier to get? I've paid for custom synthesis twice so far, but I can't afford it lately. Any analogue ideas, that include easier to obtain precursors. I'm guessing that no one will help, but it's worth a try. Fuck! Peace tomorrow, hell today. Love My Country, Fear My Government |
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